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                       Project on Emerging NanoTechnologies Current Medical Application
 
                         
                          
 
 
NanoMedical
 
 
 
Often Hailed as a Revolutionary New Technology,
Nanotechnology Has the Potential to Impact Almost Every Area of Society
 
 
 
 
The National Nanotechnology Centre (Nanotec) yesterday unveiled its
latest invention, a nanofibre net that can kill malaria carrying mosquitoes
within six minutes of their contact with it.
 
 
 
 
T-Cell Based Delivery Systems and New Imaging Options Push Field Forward
 
  
  
 
 
The studies introduce new approaches that are considered "green" nanobiotechnology
because they use no artificial compounds.
 
 
 
 
Clinical trials using patients’ own immune cells
to target tumors have yielded promising results
 
 
 
 
Demonstrated that mesoporous silica nanoparticles (MSNs), can store
and deliver chemotherapeutic drugs in vivo and effectively suppress tumors in mice
 
 

 

Smart UnderWear: 

Monitoring & Treating Medical Conditions

 

 

 

 

 

NanoTech & Stem Cells Regenerate Arteries 

A combination of nanotechnology and adult stem cells

has been shown to destroy arterial plaque atherosclerosis in the hearts of pigs

 

 

 

New ' Fuzzy Fiber ' Could Help Glaucoma Sufferers 

A futuristic fabric originally developed for use in the aviation and

energy industries could find use in treating advanced glaucoma, researchers said

 

 

 

To Attack H1N1, Other Flu Viruses, Gold NanoRods Deliver Potent Payload

Future pandemics of seasonal flu, H1N1 and other drug-resistant viruses may be thwarted

by a potent, immune-boosting payload that is effectively delivered to cells by gold nanorods

 

 

 

New Arsenic NanoParticles Blocks Aggressive Breast Cancer

researchers took a drug therapy proven for blood cancers but ineffective against solid tumors,

packaged it with nanotechnology and got it to combat an aggressive type of breast cancer

prevalent in young women, particularly young African-American women.

 

 

 

NanoBlasts from Laser Activated NanoParticles Move Molecules, Proteins & DNA into Cells 

Using chemical “nanoblasts” that punch tiny holes in the protective membranes of cells, researchers

have demonstrated a new technique for getting therapeutic small molecules,

proteins and DNA directly into living cells.

 

 

 

NanoMagnets Remove Pathogens From Blood 

Wendelin Stark/Associate Professor Institute of Chemical & BioEngineering

ETH Zurick

 

 

 

Drug Delivery System Developed Using NanoParticles Triggered 

by Electromagnetic Field

A new system for the controlled delivery of pharmaceutical drugs has been

by a team of University of Rhode Island chemical engineers using nanoparticles

embedded in a liposome that can be triggered by non-invasive electromagnetic fields

 



Israel " Virtual Patient Engine " Designs Safe Clinical Trials

and Saves Lives
Optimata/Israel

 


 

NanoTechnology Creates Artificial Artery for Clinical Trials

London Royal Free Hospital/George Hamilton
 

 
 
 
 
To Target and Kill Tumors
University of California
Michael Sailor Professor Chemistry and BioChemistry
Ji Ho Park Graduate Student
 
            
 
with NanoTechnology
University College London
NanoTechnology & Regenative Medicine
Professor Alexander Seifalian
Professor George Hamilton
 
 
 
Synthetic Platelets Halve Clotting Time
Case Western Reserve University
Erin Lavik
 
 
 
Caused by Resistant Staph Bacteria
Albert Einstein College of Medicine
 
 
 
 
University of California/Santa Barbara
University of Michigan
 
  
 
Professor Mike Stratton BBC  Video
 
First Comprehensive Analysis of Two Cancer Genomes
Wellcome Trust Sanger Institute
 
 
 
 
Prasad, Distinguished Professor of Chemistry, Samuel P. Capen Chair of Chemistry, and Director of the Institute for Lasers, Photonics, and Biophotonics (ILPB) at the University at Buffalo, together with a team of collaborators from ILPB, the Department of Medicine at Buffalo General Hospital, and the Institute of Optoelectronics at Shenzhen University in China
 
 
 
Duke University Medical Center
Bryan Clary M.D.
 
 
 
 
BioEngineered Vaccines and Magnetic NanoDiscs Show Promise
Scientific American
 
 
 
 
National Institute of Health
National Network of NanoMedicine Development Centers ( 8 )
 
1. Georgia Tech, Research Group / Bao, Gang / NanoMedicine Center for Nucleoprotein Machines / Progress Report 2009
 
2. University of Cincinnati / Guo, Peixuan / PHi 29 DNA - Packaging Motor for NanoMedicine / Progress Report 2009
 
3. University of California LA. / Ho, Chih-Ming / Center for Cell Control / Progress Report 2009
 
4. University of California LBNL / Isacoff, Ehud / NDC for the Optical Control of Biological Function / Progress Report 2009
 
5. Baylor College of Medicine TX / Chiu, Wah / Center for Protein Folding Machines / Progress Report 2009
 
6. University of Illinois Urbana / Jakobsson, Eric, G. /  Design of Biomimetric NanoConductors / Progress Report 2009
 
7. University of California S.F. / Lim, Wendell, A. / Engineering Cellular Control Synthetic Signaling and Motility Systems / Progress Report 2009
 
8. Columbia University Morningside, N.Y. / Sheetz, Michael /  Mechanics in Regenerative Medicine /
 Progress Report 2009
 
 
 
 
 
 
Understanding Cancer Series: NanoDevices (slide show) 2-22
 
 
 
 
 
BLADDER
 
 
NanoTechnology Delivers - First Report on Targeted Killing of Tumor Cells (article)
 
Bhirde AA, Patel V, Gavard J, Zhang G, Sousa AA, Masedunskas A, Leapman RD, Weigert R, Gutkind JS, Rusling JF. Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery. ACS Nano. 2009 Feb 24;3(2):307-16.
 
 
Selenium May Prevent High Risk Bladder Cancer (article)
 
Wallace K, Kelsey KT, Schned A, Morris JS, Andrew AS, Karagas MR. Selenium and risk of bladder cancer: a population-based case-control study. Cancer Prev Res (Phila Pa). 2009 Jan;2(1):70-3.
 
 
New Risks for Bladder Cancer Identified by
Massachusetts Institute of Technology Team (article)

 

Authors of the paper from MIT are Tannenbaum, Paul L. Skipper, a BE principal research scientist, and Jinping Gan, a former graduate student. Their colleagues Manuela Gago-Dominguez, Kazuko Arakawa, Ronald K. Ross, and Mimi C. Yu are at the University of Southern California, Los Angeles.

 
 
Alkylaniline-Hemoglobin Adducts and
Risks of Non-Smoking Related Bladder Cancer (pdf)
 
Jinping Gan, Paul L. Skipper, Manuela Gago-Dominguez, Kazuko Arakawa, Ronald K. Ross, Mimi C. Yu, Steven R. Tannenbaum

Affiliations of authors: Biological Engineering Division, Massachusetts Institute of Technology, Cambridge, MA (JG, PLS, SRT); Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles (MGD, KA, RKR, MCY)

 
 
 
Brain
 
NanoTechnology Combats Fatal Brain Infections (pdf)
 
Minute Antibacterial Particles Destroy Drug Resistant Germs
Institute of BioEngineering and NanoTechnology Singapore
 
 L. Liu, K. Xu, H. Wang, J. P. K. Tan, W. Fan, S. S. Venkatraman, L. Li and Y. Yang,
 
Toward A NanoMedicine for Brain Cancer (abstract)
 
ACS Publications
Argonne National Lab, University of Chicago
A High Performance NanoBio Photocatalyst for Targeted Brain Cancer Therapy
Elena A. rozhkova, LLya Ulasov, Barry Lai, Nada M. Dimitrijevic, Maciej S. Lesniak, Tijana Rajh
 
NanoTechnology Solutions for Alzheimer's Disease (abstract)
 
Advances in Research Tools, Diagnostic Methods and Therapeutic Agents
IOS Press
Journal of Alzheimer's Disease
 
 
Targeted NanoMedicine: Effective Treatment Modalities
for Cancer, AIDS, and Brain Disorders (article)
 
Medscape
Madaswamy S. Muthu,1 Sanjay Singh 2
1Department of Pharmacology, Institute of Medical Sciences, 2Department of Pharmaceutics,
 Institute of Technology, Banaras Hindu University, Varanasi, India
http://www.medscape.com/viewarticle/587001
 
 
Breast
 
 
New Arsenic NanoParticle Blocks Aggressive Breast Cancer
 
NanoTechnology for Breast Cancer Therapy (pdf)
BioMedical MicroDevices Journal Article
Takemi Tanaka, Paolo Decuzzi, Massimo Cristofanilli, Jason H. Sakamoto, Ennio Tasciotti,
Fredika M. Robertson, Mauro Ferrari
 
 
Los Alamos National Lab (article)
Breast Cancer Screening
Safer, More Comfortable and Accurate Test Finds Undetectable, Highly Fatal Cancers
 
Radiation Breakthrough Gives Breast Cancer Patients Hope in Single Dose (article)
Intraoperative Radiation Therapy for Breast Cancer
Cancer Treatment Centers of America Philadelphia
 
Inorganic NanoParticles for Predictive Oncology of Breast Cancer (article)
Medscape
Future Medicine Ltd
Maksym Yezhelyeu, Rami Yacoub, Ruth O'Regan
 
 
Colon and Rectal
 
Science Translational Medicine Reports First Successful Treatment for Me'ne'trier Disease (article)
Robert Coffey M.D. Assistant Professsor Division of Gastroenterolgy
Haley Fiske M.D. Assistant Professor  Division of Gastroenterology

Other co-authors: Jarred Tanksley, Ki Taek Nam, Ph.D., James Goldenring, M.D., Ph.D., Robbert Slebos, Ph.D., Daniel Liebler, Ph.D., Amir Abtahi, Bonnie La Fleur, Ph.D., Gregory Ayers, Christopher Lind, M.D., and Mary Washington, M.D., Ph.D.

 
Epigenetics vs Gene Mutations in Colorectal Cancer (article)
The Sidney Kimmel Comprehensive Cancer Center
John Hopkins University
Stephen B. Boylin M.D.
 
 
Kidney
 
The Role of Bottom-Up NanoTechnology in Kidney Disease (article)
Medscape
An Expert Commentary by Allen R. Nissenson M.D.
 
 
 
 
Liver
 
Telomeres Are Shorter in Liver Cancer Tissue Than Non-Tumor Tissue
National  Institute of Environmental Health Sciences
Columbia University Mailman School of Public Health
Regina M. Santella, PhD
 
 
Inflammatory Protein May Be Why Liver Cancer
is More Prevalent in Men Than Women
National Institute of Environmental Health Sciences
University of California, S.D.
Michael Karin PhD
 
 
Lung
 
Gene May Be Linked to Lung Cancer
National Institute of Environmental Health Sciences
University of Cincinnati
Marshall Anderson, PhD
 
 
New DNA Test Uses NanoTechnology to Find Early Signs of Cancer
John Hopkins
 
 
 
Pancreatic
 
Molecular Predictor of Prognosis for Pancreatic Cancer Patients Identified
 
National Institute of Environmental Sciences
University of Texas MD, Anderson Cancer Center
Melissa Bondy PhD
 
Emerging Therapies in Pancreatic Cancer Show Promise (article)
International Conference in Molecular Targets and Cancer Therapeutics
Craig Thompson M.D. Director of the Abramson Cancer Center, University of Pennsylvania
 
 
Prostate
 
 
Bisphenol A Effects on Estrogen Receptor (13) Expression:
Implications in Prostate Cancer
University of Cincinnati, College of Medicine
Janet K. Hess-Wilson, Shuk-Mei Ho PhD, Karen E. Knudsen, PhD
 
 
Birch-Bark Extract, Betulinic Acid, Inhibits Prostate Cancer Growth
National Institute of Environmental Health Sciences
Texas A&M University Health Science Center
Stephen Safe PhD
 
 
Prostate Cancer Linked to High Levels of a Mismatch Repair Protein
National Institute of Environmental Health Sciences
Wake Forest University School of Medicine
Alixanna M. Norris
 
 
DNA Coated NanoTubes Help Kill Tumors Without Harm to Surrounding Tissue
Wake Forest University School of Medicine
Ralph D’Agostino Jr., Ph.D., John Olson, M.S., Evan Gomes, Ph.D., and doctoral student Supratim Ghosh, all of the School of Medicine; Samrat Dutta and Martin Guthold, Ph.D., of the Wake Forest University Department of Physics, and David L. Carroll, Ph.D., director of the Wake Forest University Center for Nanotechnology and Molecular Materials.
 
Increased Heating Efficiency and Selective Thermal Ablation of Malignant Tissue with DNA Encased Multiwalled Carbon NanoTubes (full text) ACS Nano
Supratim Ghosh, Samrat Dutta, Evan Gomes, David Carroll#, Ralph D’Agostino, Jr.§, John Olson, Martin Guthold and William H. Gmeiner* Department of Cancer Biology Program in Molecular Genetics§ Department of Biostatistical Sciences
Center for Biomolecular Imaging, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157
Department of Physics# Center for Nanotechnology and Nanomaterials, Wake Forest University, Winston-Salem, North Carolina 27109
 
 
NanoParticle Based Bio-Barcode Assay Redefines 'undetectable' PSA and Biochemical Recurrence After Radical Prostatectomy (abstract)
PNAS
Northwestern University
C.Shad Thazton, Robert Elghanian, Audrey D. Thomas, Savka L. Stoeva, Jae-Seung Lee, Norm D. Smith, Anthony J. Schaeffer, Helmut Klocker, Wolfgang Horninger, George Bartsch, Chad A. Mirkin
 
 
NanoTechnology Enhances Early Detection of Prostate Cancer in Black Males (article)
Medscape Hermatology-Oncology
Roxanne Nelson
 
 
 
Skin
 
 
Ben-Gurion University Researchers Develop New Device That Enables Early Detection of Cancerous Skin Tumors (article0
American Associates
Ben-Gurion University of the Negev
 
Green Tea and Skin Cancer (article)
National Institute of Environmental Health Sciences
University of Alabama, Birmington
Santosh K. Katiyar PhD